The objective of this study was to examine the quantity of three periodontal pathogens, including Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia, between smokers and non-smokers in the Electrical Generating Authority of Thailand. The study participants included 244 smokers and 244 non-smokers. All of them were male, aged 41-60 years old (average 48.2±4.4). The quantitative analysis of periodontal pathogens was performed using real-time PCR. The results showed that smokers had significantly higher prevalence and quantity of P.gingivalis in subgingival plaque than non-smokers. Logistic regression analysis showed that after adjusting for periodontitis, smokers were 1.6 times more likely to harbor P. gingivalis than non-smokers. The relationship between smoking and periodontal pathogens was more evident in the subgroup analysis of non-periodontitis subjects. In this subgroup, smokers had an increased risk for having P. gingivalis and T. forsythia by 2.4 times and 2.1 times, respectively. We conclude that smoking significantly affects the microbial composition of subgingival plaque, which could consequently contribute to an increased risk for periodontitis in smokers.
SUBJECT
โรคปริทันต์อักเสบ
จุลินทรีย์
แบคทีเรีย
LOCATION
CALL#
STATUS
Thailand and ASEAN Information Center (6th Floor) : Chula Collection