AuthorMartin, Yvonne Connolly, 1936-
TitleQuantitative drug design [electronic resource] : a critical introduction / Yvonne Connolly Martin
Imprint Boca Raton : CRC Press/Taylor & Francis, c2010
Edition 2nd ed
Connect tohttp://marc.crcnetbase.com/isbn/9781420071009
Descript xv, 282 p. : ill

CONTENT

Overview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations that relate potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems


Drugs -- Structure-activity relationships QSAR (Biochemistry) Drugs -- Design Electronic books.