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TitlePharmacokinetics in drug discovery and development [electronic resource]
Author edited by Ronald D. Schoenwald
Imprint Boca Raton : CRC Press, c2002
Connect tohttp://marc.crcnetbase.com/isbn/9781420010084
Descript 426 p. : ill

CONTENT

Machine generated contents note: SECTION I Basic Principles -- Chapter 1 Basic Principles3 -- Ronald D. Schoenwald -- SECTION II Industrial and Regulatory Applications -- Chapter 2 PK/PD Approach33 -- Honghui Zhou -- Chapter 3 Pharmacokinetics and Metabolism in Drug Discovery -- and Preclinical Development57 -- Nishit B. Modi -- Chapter 4 Phase I, II, and III FDA Submissions 73 -- Mark G. Eller -- Chapter 5 Bioavailability and Bioequivalence 97 -- Veneeta Tandon -- SECTION III Clinical Applications -- Chapter 6 General Approaches to Clinical Pharmacokinetic Monitoring 115 -- Ronald A. Herman -- Chapter 7 Aminoglycosides and Other Antibiotics 127 -- Michael E. Klepser and Erika J. Ernst -- Chapter 8 Cardiovascular Agents139 -- John M. Dopp and Bradley G. Phillips -- Chapter 9 Psychotropic Agents 171 -- Paul J. Perry -- Chapter 10 Theophylline201 -- Bernd Meibohm -- Chapter 11 Anticonvulsant Agents 231 -- Gail D. Anderson -- SECTION IV Research Applications -- Chapter 12 Classical Modeling267 -- David W A. Bourne -- Chapter 13 Noncompartmental Modeling: An Overview 283 -- Ronald A. Herman -- Chapter 14 Physiologically Based Pharmacokinetic Models 295 -- James M. Gallo -- Chapter 15 Population Pharmacokinetics315 -- Jeffrey S. Barrett -- Chapter 16 The Linear Systems Approach 357 -- Peter Veng-Pedersen -- Index415


Pharmacokinetics Drug development Electronic books.



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