Objectives: To study the result of self-monitoring of blood glucose (SMBG) on clinical outcomes and glycemic management in insulin-treated type 2 diabetic patients with uncontrollable blood glucose level at Lad-yao hospital. Methods: A total of 72 insulin-treated type 2 diabetic patients were enrolled in the study. 36 patients were randomized into the study group and control group. patients in the study group were trained to perform SMBG and recorded their blood glucose level, meanwhite the control group received normal monitoring at diabetic clinic. During the study period, patients in both groups were followed up by telephone for advice once a week. This study was conducted during December 2008 to March 2009. Results: There were no difference (p>0.05) in baseline patient demographics. After 3-month of study, the patients in the study group with SMBG intervention had statistically significant differences in hemoglobin A₁c (A1C:p<0.001) and fasting plasma glucose (FPG:p<0.05) between the beginning and the end of the study. In the control group, there was a significant change for A1C(p<0.001) but not for FPG (p=0.581). However, no differences in A1C and FPG changes between the groups (p>0.05) were found at the end of the study. Conclusions: Patients with uncontrolled blood glucose who used SMBG achieved significantly improved A1C and FPG during the short-term follow up. However, patients in the control group also improved in glycemic control too. The possible explanation of this result is close monitoring by pharmacist in both groups made patients wanting and willing to participate in diabetic treatment and in turn they tried to manage themselves by tightening their glycemic controls.
