Title | The laboratory mouse [electronic resource] / edited by Hans J. Hedrich and Gillian Bullock |
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Imprint | Amsterdam ; Boston : Elsevier Academic Press, c2004 |
Connect to | http://www.sciencedirect.com/science/book/9780123364258 |
Descript | xvi, 600 p. : ill |
History, Development and Genetics of the Mouse as a Laboratory Model -- Origin of the Laboratory Mouse and Related -- Historical Foundations -- Strain, Stock and Mutants -- Mouse Genomics -- Generation of Mouse Mutants by Sequence Information Driven and Random Mutagenesis -- The Mouse as an Animal Model for Human Diseases -- The Mouse in Preclinical Safety Studies -- Anatomy and Developmental Biology -- Gross Anatomy -- Normative Histology of Organs -- Imaging -- Introduction to Early Mouse Development -- Pathophysiology (including non-infectious diseases) -- Skin and Adnexes of the Laboratory Mouse -- Cardiovascular System -- Respiratory Tract -- Gastrointestinal System and Metabolism -- Inbred Mouse Models for Autoimmune Disease -- Hematology of the Mouse -- The Social Behaviour of Mice and its Sensory Control -- Neuroendocrine Immune Network in Stress -- Circadian Rhythms of the Mouse -- Gerontology -- Diversity of Spontaneous Neoplasms in Commonly Used Inbred Strains and Stock of Laboratory Mice -- Infectious Agents and Diseases -- Viral Infections -- Animal Husbandry and Production -- Housing and Maintenance -- Gnotobiology and Breeding Techniques -- Assisted Reproduction and Cryopreservation -- Health Monitoring -- Nutrition of Laboratory Mice -- Procedures -- Legal Regulations for the Protection of Animals Used for Scientific Experiments -- Necropsy Methods -- Handling and Restraint -- Routes of Administration -- Collection of Body Fluids -- Anaesthesia, Analgesia and Euthanasia