Title | In vitro methods in pharmaceutical research [electronic resource] / edited by Josโe V. Castell and Marโia Josโe Gโomez-Lechโon |
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Imprint | San Diego : Academic Press, c1997 |
Connect to | http://www.sciencedirect.com/science/book/9780121633905 |
Descript | ix, 467 p. : ill |
D.W. Straughan, J.H. Fentem, and M. Balls, Replacement Alternative and Complementary In Vitro Methods in Pharamaceutical Research. -- M.D. Barratt and M. Chamberlain, Integration of QSAR and In Vitro Toxicology. -- F.A. Barile, Continuous Cell Lines as a Model for Drug Toxicity Assessment. -- P. Bach, In Vitro Models for Nephrotoxicity Studies. -- A.E.M. Vickers, Experimental In Vitro Models to Evaluate Hepatotoxicity. -- M.J. Gomez-Lechon, T. Donato, X. Ponsoda, R. Fabra, R. Trullenque, and J.V. Castell, Isolation, Culture and Use of Human Hepatocytes in Drug Research. -- E. McFarlane-Abdulla, and I.C. Campbell, Studies of Nephrotoxicity in Cellular Studies. -- M. Adolphe, S. Thenet-Gauci, and S. Demignot, Chondrocyte Culture: A Target System to Evaluate Pharmaco-Toxicological Effects of Drugs. -- E. Chacon, D. Acosta, and J.J. Lemasters, Primary Cultures of Cardiac Myocytes as In Vitro Models for Pharmacological andToxicological Assessments. -- R. Roguet, Cutaneous Pharmacotoxicology In Vitro. -- H. Spielmann, Ocular Irritation. -- M.A. Miranda, Phototoxicity of Drugs. -- I. de G. Mitchell and R.D. Combes, In Vitro Genotoxicity and Cell Transformation Assessment. -- B. Schmid, R. Bechter, and P. Kucera, The Use of Whole Embryo Cultures in In Vitro Teratogenicity Testing. -- J.V. Castell, M.J. Gomez-Lechon, X. Ponsoda, and R. Bort, In Vitro Investigation of the Molecular Mechanisms of Hepatotoxicity. -- A. Guillouzo, Biotransformation of Drugs by Hepatocytes. -- K. Mace, E.A. Offord, and A.M.A. Pfeifer, Drug Metabolism and Carcinogen Activation Studies with Human Genetically Engineered Cells