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TitleAdvances in medicinal chemistry. Volume 3 [electronic resource]
Imprint [S.l.] : Elsevier Science, 1995
Connect tohttp://www.sciencedirect.com/science/publication?issn=10675698&volume=3
Descript 1 v

SUMMARY

Volume 3 of Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophrenia. Chapter 2 relates an account on the discovery of novel antithrombotic drugs based on the RGD motif through a rational design approach. Chapter 3 presents the medicinal chemistry and preclinical development surrounding sertraline, a very important serotonin reuptake drug for the treatment of endogenous depression. Finally, Chapter 4 gives a summary of a series of boronic acid-based immunosuppressants that operate via inhibition of dipeptidypeptidase IV


Pharmaceutical chemistry Electronic books.



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