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AuthorKenakin, Terrence P
TitleA pharmacology primer [electronic resource] : theory, applications, and methods / Terry Kenakin
Imprint Amsterdam ; Boston : Elsevier Academic Press, c2006
Edition 2nd ed
Connect tohttp://www.sciencedirect.com/science/book/9780123705990
Descript xviii, 299 p. : ill. (some col.), ports. ; 28 cm

SUMMARY

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. *Over 30 new figures and tables *More human interest information to provide readers with historical facts on pharmacology research *New section on therapeutics to help identify diseaes and drug treatments *New section on new biological concepts relevant to pharmacological research (i.e., systems biology) *New study sections organized with ASPET and other international pharmacology organizations *New coverage of pharmacokinetics and drug disposition


CONTENT

What is Pharmacology? -- How Different Tissues Process Drug Response -- Drug Receptor Theory -- Pharmacological Assay Formats: Binding -- Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- Orthosteric Drug Antagonism -- Allosteric Drug Antagonism -- The Process of Drug Discovery -- Target- and System-based Strategies for Drug Discovery -- Hit to Drug: Lead Optimization -- Statistics and Experimental Design -- Selected Pharmacological Methods -- Glossary of Pharmacological Terms -- Appendices: -- Statistical Tables -- Mathematical Fitting Functions


Receptors Drug -- physiology Dose-Response Relationship Drug Pharmacology -- methods Pharmacology Drugs Chemicals -- Physiological effect Pharmacologie Mโedicaments Produits chimiques -- Effets physiologiques Electronic books.



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