Author | Kenakin, Terrence P |
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Title | A pharmacology primer [electronic resource] : theory, applications, and methods / Terry Kenakin |
Imprint | Amsterdam ; Boston : Elsevier Academic Press, c2006 |
Edition | 2nd ed |
Connect to | http://www.sciencedirect.com/science/book/9780123705990 |
Descript | xviii, 299 p. : ill. (some col.), ports. ; 28 cm |
What is Pharmacology? -- How Different Tissues Process Drug Response -- Drug Receptor Theory -- Pharmacological Assay Formats: Binding -- Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- Orthosteric Drug Antagonism -- Allosteric Drug Antagonism -- The Process of Drug Discovery -- Target- and System-based Strategies for Drug Discovery -- Hit to Drug: Lead Optimization -- Statistics and Experimental Design -- Selected Pharmacological Methods -- Glossary of Pharmacological Terms -- Appendices: -- Statistical Tables -- Mathematical Fitting Functions