Author	Kenakin, Terrence P
Title	A pharmacology primer [electronic resource] : theory, applications, and methods / Terry Kenakin
Imprint	Amsterdam ; Boston : Elsevier Academic Press, c2006
Edition	2nd ed
Connect to	http://www.sciencedirect.com/science/book/9780123705990
Descript	xviii, 299 p. : ill. (some col.), ports. ; 28 cm

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. *Over 30 new figures and tables *More human interest information to provide readers with historical facts on pharmacology research *New section on therapeutics to help identify diseaes and drug treatments *New section on new biological concepts relevant to pharmacological research (i.e., systems biology) *New study sections organized with ASPET and other international pharmacology organizations *New coverage of pharmacokinetics and drug disposition

What is Pharmacology? -- How Different Tissues Process Drug Response -- Drug Receptor Theory -- Pharmacological Assay Formats: Binding -- Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- Orthosteric Drug Antagonism -- Allosteric Drug Antagonism -- The Process of Drug Discovery -- Target- and System-based Strategies for Drug Discovery -- Hit to Drug: Lead Optimization -- Statistics and Experimental Design -- Selected Pharmacological Methods -- Glossary of Pharmacological Terms -- Appendices: -- Statistical Tables -- Mathematical Fitting Functions