I. Breast anatomy and development -- II. Diagnosis and management of benign breast diseases -- III. Breast imaging and inage-guided biopsy techniques -- IV. Epidemiology and assessing and managing risk -- V. In situ carcinoma -- VI. Pathology and biological markers of invasive breast cancer -- VII. Management of primary invasive breast cancer -- VIII. Preoperative systemic therapy -- IX. Special therapeutic problems -- X. Evaluation after primary therapy and management of recurrent breast cancer -- XI. New breast cancer therapeutic approaches --XII. Site-Specific therapy of metastatic breast cancer -- XIII. Breast cancer in special populations -- XIV. Issues in breast cancer survivorship -- XV. Other considerations