In this work, the selective oxidation of sulfur compounds catalyzed with titanocene was studied. The sulfur compounds studied are diethyl sulfide, thiophene, benzothiophene, dibenzothiophene. The experimental results revealed that titanocene could catalyze the conversion of sulfur compounds to yield sulfoxide and sulfone in high activity and selectivity. Parameters affecting the reaction were investigated: amount of catalyst, amount of oxidizing agent, additive, solvent, time and temperature. The optimum condition for diethyl sulfide oxidation was at-20 ํC, 4 hrs, titanocene 0.136 mmol, oxidizing agent 1 mmol, with molecular sieve as an additive, and dichloromethane as solvent. For thiophene, benzothiophene and dibenzothiophene, the optimum condition was at 30 ํC, titanocene 0.27 mmol, oxidizing agent 2 mmol, with molecular sieve as additive, and dichloromethane as solvent. In addition, the rate of reaction was determined and found that the order ofreaction rate was: diethyl sulfide > thiophene > benzothiophene > dibenzothiophene, which was due to the steric hindrance of catalyst.