To study the gastroprotective and antioxidant effects of turmeric oil. Gastroprotective effect was done in rat’s model by using 0.6N HCI and indomethacin as ulcer agents. Turmeric oil was given orally to rat at doses of 0.075,0.15, and 0.3 g/kg 30 minutes prior to experimental induced ulcer. Gastroprotective mechanism of turmeric oil was examined by using ulcer index as measuring gastric pH, pepsin activity and gastric wall mucus content. Antioxidant of turmeric oil was studied by using Thin Layer Chromatography (TLC) method and spectrophotometric assay of 2, 2-diphenyl-1-picrylhydrazyl (DPPH) at lambda =517 nm. Measurement of superoxide dismutase (SOD) and lipid peroxidation in same groups of ulcer inducing rats were also determined. Turmeric oil 0.3 g/kg exhibited a significant gastroprotection against ulcerative condition. The values of 97.41% and 100% ulcer inhibition were obtained in HCI model and indomethacin medel respectively, compared to control. These dises were comparable to atropine sulphate 1.25 mg/kg and misoprostol 100 microgram/kg respectively.Three oral doses of turmeric oil could reduce pH of gastric acid from 2.5+-0.53 to 2.7+-0.48, 3.0+-0.00, 3.5+-0.52 respectively, reduce pepsin activity 4.8+-25.21, 12.7+-27.82, 62.6+-12.94% and increase gastric wall mucus content 23.3+-2.61, 59+-6.95% accordingly. Turmeric oil showed less antioxidation property by TLC method, which conformed to the spectrophotometric assay of 36.7% radical scavenging properties compared to 95.1% of gallic acid and 94.8% of 3-tert-butyl-4-hydroxyanisole (BHA) standard reference at 1000 ppm. Treatment of turmeric oil could reduce lipid peroxidation on HCI induced ulcer to range 8.67+-0.28, 7.65+-0.76 and6.69+-0.32 nmol/mg protein in serum compared to control 10.97+-2.01 nmol/mg protein and 10.20+-0.65, 9.59+-1.69 and 8.10+-0.92 nmol/mg protein in tissue compared to control 13.39+-1.38 nmol/mg protein. Increased SOD 12.98+-0.86, 15.13+-0.12 and 16.84+-1.53 units/mg protein in serum compared to control 10.90+-0.70 units/mg protein and 22.90+-2.04, 23.13+-0.98 and 23.91+-1.40 units/mg protein in tissue compared to control 18.65+-1.86 units/mg protein. Turmeric oil could reduce lipid peroxidation in serum on indomethacin induced ulcer 6.49+-0.52 nmol/mg protein compared to control 12.14+-0.83 nmol/mg protein and 4.56+-0.71 nmol/mg protein compared to control 9.53+-0.44 nmol/mg protein in tissue, and the turmeric oil treated at dose of 0.3 g/kg could increase SOD in indomethacin induced ulcer 11.05+-0.94 units/mg protein in serum compared to control 8.71+-2.48 units/mg protein and 26.15+-2.84 units/mg protein in tissue compared to control 9.92+-1.93 units/mg.