The purpose of this survey research was to study two groups of working mothers who had different working schedules. The comparision between Cabin Attendants and Ground Officers regarding their interaction to infant, infant development, and time spent on infant caregiving were examined. The study involved a sample of 60 pairs of mothers and infants, with the mothers’ age ranging from 27-40 years. All infants were their mothers' first child, with their age ranging from 7 -18 months. All mothers were staff members of Thai Airways International Public Co., Ltd. The instruments used were Denver II (Frankenberg & Dodds, 1990), Nursing Child Assessment Teaching Scales (Barnard, 1978) and an interview form. T-Test and Pearson’s Correlation were utilized for data analysis. The results were as follows: There was no difference between Cabin-Attendant mothers and Ground-Officer mothers regarding their overall interaction to infants. Differences on caregiving time for their infants and infant development between these two groups of mothers were not found in this study. Finally, the study showed no correlations between the scores of maternal interaction to their infants and the amount of time spent on infant caregiving.