The dengue virus protease complex NS2B/NS3-A novel target for the structure-based design of improved antiviral agents / Gerd Katzenmeier ; co-investigator, Chanan Angsuthanasombat
Imprint
Bangkok : Thailand Research Fund, 2001
Descript
48 leaves : ill., charts ; 30 cm
CONTENT
Flaviviraidae -- Aedes aegypti -- Aedes albopictus -- NS3 proteolytic activity -- Cloning, overexpression and development of purification methods for the NS2B/NS3 two-component protease -- Development of an enzymatic assay for the NS3 protease and evaluation of substrates -- Collection of initial kinetic and mechanistic data for the enzyme