This research investigated the removal of nickel from synthetic wastewater using an Iron-Waste column. The experiment was divided into two parts. The first one was continuous column experiment and the others was batch experiment. The continuous column was used to study effect of Iron-Waste height and effect of flow to removal efficiency. The batch experiment was used to study effect of pH, dissolve oxygen, anion which was used sulfate and chloride ions to study and cation which was used zinc and copper ions to study For continuous column, It was found that the height of Iron-Waste had rerated to nickel removal efficiency. When the height was increased the removal efficiency would be increased too but if the height was too high it would have clogging problem very easily. For the effect of flow, it was found that the increasing of flow was reduced removal efficiency. When the nickel was added to the system with concentration of 11.14 mg/l, the average effluent concentration was 0.30, 0.77, 1 90 and 2.94 mg/l or be calculated เท percentage was 97.3%, 93.1%, 82.9% and 73.6% at the flow of 0.5, 1.0, 1.5 and 2.0 BV/Hr respectively for 91 days operation. For batch experiment, it was found that pH was the very important parameter to removal efficiency. The efficiency was varied rapidly in narrow pH range. It was changed from less than 10% at pH below 4 to be more than 90% at pH over 8. For dissolve oxygen it was also effected to the removal efficiency by the removal rate was depend on concentration of dissolve oxygen. In the aerated status, when dissolve oxygen concentration was nearly to saturated point it would be the highest removal rate in this experiment. For the effected of anion, sulfate and chloride ions was increased the efficiency a little bit. And the last one for the cation, zinc and copper was almost no effect with the efficiency. From the experiment, the mechanism to remove nickel may be adsorption .