การเปรียบเทียบความชุกของเชื้อซัลโมเนลลาที่ไม่ใช่ไทฟอยด์ ในอุจจาระของผู้ป่วยโรคลูปุสกับคนปกติ / จีรภัทร วงศ์ชินศรี = The comparison of prevalence of positive stool culture for non-typhoidal salmonella in systemic lupus erythematosus with normal population / Jeerapat Wongchinsri
Compares the prevalence of positive stool culture for non-typhoidal salmonella in systemic lupus erythematosus (SLE) with normal population. Three stool specimens of each SLE patient and normal control were cultures for non-typhoidal salmonella at the Department of Microbiology, Faculty of Medicine, Chulalongkorn University. The results were compared between 2 groups. In the SLE group, the details about disease duration, evidence of kidney involvement and the treatment status were also recorded. There were 110 valuable subjects in each group, SLE patient and normal control. The demographic data was not significantly different between these two groups. In SLE group, there were many variety of the disease status organ involvement and the treatment status. The positive stool culture for non-typhoidal salmonella in the SLE group was significantly higher than the control group [42 cases (38.2%) vs 25 cases (22.7%); p = 0.009]. The most common group in SLE patient was salmonella group E. The positivity of stool culture was significantly determined by presence of lupus nephritis but was not influenced by disease duration, the dosage of corticosteroid and the presence of immunosuppressive treatment. Thes study has shown that there are higher prevalence of positive stool culture for non-typhoidal salmonella in SLE patient than normal population. The result of both groups was not depend on age, sex, education, occupation and the income level. In SLE group, the prevalence of this organism was significantly determined by the presence of lupus nephritis, but was not influenced by disease duration, or the treatment regimen.