At present chemical industries have invented new processes and improved old processes to obtain high quality and capacity of production and to reduce cost and emission from the production. In this research, a packed distillation column that used raschig ring bed was simulated by Aspen V.10. The research was divided into three steps. First, build the model satisfied with the result from the experiment. With shortcut design simulation, it gave the murphree efficiencies of the experimental column to be equal to 32.13% and that with rigorous column simulation to be equal to 53.95%. Second, dynamic simulations for the startup period were performed to search for an optimal process trajectory with minimum expense. It was found that the optimal heating rate at the reboiler should be 2.40 ํC/min for duration of 30 minutes. After that the heating rate would be adjusted so that the temperature of 122 ํC was reached within 12 minutes. The final step, construct and tune the LV configuration control system for controlling the temperatures of the top and bottom stages. The model was tested. It was found that the system was stable and by increasing the flow rate of feed stream, the controlled temperatures moved back to steady state condition 9% and 61% faster than the column without the control system, respectively