The experimental design study was conducted in hypertensive outpatients of Vachira Phuket Hospital for the purpose of evaluating the outcomes of patient education by pharmacist on clinical and quality of life aspects. Total of 120 patients were divided into study group (with patient education provided) and control group (without patient education provided) each of 60 patients randomly assigned, with six month period of studies. Average age of study group and control group were 66.3+-10.0 and 67.3+-11.0, respectively. It was found that systolic blood pressure in study group compared before and after patient education was significantly decreased (p<0.05) from 145.0+-15.5 to 138.5+-13.9 mm.Hg while was not significantly decreased in control group (from 145.4+-15.6 to 144.9+-21.3 mm.Hg). Drug use compliance was also significantly increased (p<0.05) in study group from 25 to 52 percent but not significantly different in control group. According to life-style modification in high sodium and cholesterol intake, itwas significantly decreased (p=0.028 and p=0.034) from 91.7% and 81.7% to 50.0% and 66.0% respectively in study group. The quality of life assessment by using SF-36 Questionnaire was not significantly different (p>0.05) in both groups related to mean score calculated. However, trends of higher quality of life after patient education was shown in study group. The percentage of patients with self-stopped treatment in study group due to adverse drug effects was decreased from 6.7% to nil. Therefore, participation of pharmacist in patient education, especially in hypertensive patients, will benefit patient treatment and quality of life. However, quality of life studied in this work is only part of humanistic outcomes study, patient satisfaction and disease and disease management knowledge have not yet been evaluated. Development of questionnaire for humanistic outcomes study suitable for Thais should be performed and further studied to give a complete result.
