สายการสังเคราะห์ 2-พัยร์โรลิโดนที่อาจเป็นไปได้จากซังข้าวโพดเพื่อใช้ในทางเภสัชกรรม / สมเกียรติ รุจิรวัฒน์ =A possible route of synthesis of 2-pyrrolidone from corn-cob for pharmaceutical uses / Somkiat Rujirawatana
The main purpose of this research was aimed at finding the pathway for the synthesis of 2 – phrrolidone from corn – cob, which is one of the agricultural waste products. According to the research, one of the possible route of synthesis of 2 – pyrrolidone from corm – cob was through the following steps :- Step 1 Synthesis of furfural using corn – cob as the starting material yielded 4.1 g. – 5.8 g. furfural when 100 g. of dried corn – cob was used Step 2 Synthesis of 2 – furoic acid using furfural as the starting material yielded 50.2 – 61.4 % furoic acid Step 3 Synthesis of furan using furoic acid as the starting material yielded 30.0 – 34.7% furan Step 4 Synthesis of tetrahydrofuran using furan as the starting material yielded 79.1 – 85.0% tetrahydrofuran Step 5 Synthesis of γ - butyrolactone using tetrahydrofuran as the starting material yielded 20.0 – 31.0% γ - butyrolactone Step 6 Synthesis of 2 – pyrrolidone using γ butyrolactone as the starting material yielded 27.4 – 35.8% 2 – pyrrolidone All of these products synthesizes were identified by using the physical constant values along with Infrared Spectrophotometer.
