TitleEpstein's inborn errors of development : the molecular basis of clinical disorders of morphogenesis / edited by Robert P. Erickson, Anthony Wynshaw-Boris
ImprintNew York : Oxford University Press, 2016
Edition Third edition
Descript xlvii, 1497 pages : illustrations, charts ; 29 cm

CONTENT

I: General concepts -- II: Patterns of development -- III: Defined core developmental pathways linked to cilia -- A. Ciliary functions: genesis, transport, and reabsorbtion -- B. The sonic hedgehog signaling pathway -- C. The wnt signaling pathway -- D. The planar cell polarity (PCP) pathway -- IV: Other defined core developmental pathways -- A. The TGF-β‎ (Beta) signaling pathway -- B. The TNF signaling pathway -- C. The FGF signaling pathway -- D. Glial cell‒derived neurotrophic factor signaling -- E. Introduction to endothelin-B receptor and SOX10 pathways -- F. The notch signaling pathway -- G. The PI3K-LKB1 pathway -- H. The RAS/ERK/MAPK pathway -- I. Eph/ephrin signaling -- V: Transcription factors and chromatin regulators -- A. The homeobox gene family -- B. The paired box (PAX) gene family -- C. The forkhead gene family -- D. The T-Box gene family -- E. The SOX gene family -- F. Transcription factors -- G. Regulation of chromatin structure and gene expression -- VI: Cellular processes and dynamics -- A. RNA localization and control of activity -- B. Posttranslational control and ubiquitination -- C. Cell cycle, proliferation, and apoptosis -- D. Guanine nucleotide-binding proteins -- E. Microtubule motors and the cytoskeleton -- F. Vesicle-mediated trafficking and endocytosis -- G. Extracellular matrix -- H. Junctions, transporters, and channels -- VII: Dysmorphic disease genes of unknow function or unclassified


SUBJECT

  1. Genetic Diseases
  2. Inborn -- genetics
  3. Congenital Abnormalities -- genetics
  4. Morphogenesis -- genetics

LOCATIONCALL#STATUS
Medicine LibraryQZ50 E64 2016 CHECK SHELVES