Office of Academic Resources
Chulalongkorn University
Chulalongkorn University

Home / Help

AuthorMolliver, Mark E. author
TitleThe Ontogenesis of Cortical Circuitry: The Spatial Distribution of Synapses in Somesthetic Cortex of Newborn Dog [electronic resource] / by Mark E. Molliver, Hendrik Van der Loos
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg, 1970
Connect to
Descript 54 p. 27 illus. online resource


The ontogenesis of cortical circuitry is the subject of the investigation reported in this paper!. Strategie elements of cortical circuitry are synaptic contacts: sites of neuronal interaction. If we first determine the location of early formed synapยญ ses, we may then seek the pre-and postsynaptic elements, that is, the structures which meet and interact at each synaptic junction. The dynamic aspects of cortical development cannot be studied directly: neuronal growth cannot be observed in an intact brain. The pattern of developยญ ment can be approached only by the analysis of static properties at multiple ages. We have selected the newborn dog as a starting point for these studies. Our observations have been restricted to a small portion of primary somesthetic corยญ tex. This region was selected because, in mature cortex, its input and physiologie properties are relatively weIl known. It is particularly advantageous to study a primary sensory projection area because its morphologie development can be diยญ rectly related to its functional development. (A related investigation of the ontoยญ genesis of electrical activity in somesthetic cortex of the dog will be reported separately). A selective review of the literature is necessary in order to place this work in the context of a few relevant phenomena of cortical development


Methods -- Specimen preparation -- Data collection -- Data analysis -- Results -- Cytoarchitectonic pattern -- Distribution of synaptic contacts -- Identification of postsynaptic elements -- Discussion -- Summary -- References

Medicine Medicine & Public Health Medicine/Public Health general


Office of Academic Resources, Chulalongkorn University, Phayathai Rd. Pathumwan Bangkok 10330 Thailand

Contact Us

Tel. 0-2218-2929,
0-2218-2927 (Library Service)
0-2218-2903 (Administrative Division)
Fax. 0-2215-3617, 0-2218-2907

Social Network


facebook   instragram