Title	Lead molecules from natural products [electronic resource] : discovery and new trends / [edited by] Mahmud T.H. Kahn, Arjumand Ather
Imprint	Amsterdam ; Boston : Elsevier, 2006
Edition	1st ed
Connect to	http://www.sciencedirect.com/science/publication?issn=1572557X&volume=2
Descript	xviii, 430 p. : ill., ; 25 cm

Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents

Reverse Pharmacognosy. Effects of Plant Extracts on Gene Expression Profiling. Effects of Medicinal Plant Extracts on Molecular Interactions between DNA and Transcription Factors. Plants with Antitumor Properties: from Biologically Active Molecules to Drugs. Herbal Extracts and Compounds Active against Herpes Simplex Virus. Cough and its Pharmacological Modulation. Phytotherapy of the Cough. The Medicinal Potential of Black seed (Nigella sativa) and its Components. Cyclin Dependent Kinase Inhibitors from Natural Sources. Anticancer and Medicinal Properties of Essential Oil and Extracts of East Mediterranean Sage (Salvia triloba). Marine Organisms from Brazil as Source of Potential Anticancer Agents. Anticancer Potential of Northeast Brazilian Plants. Safety and Efficacy of Phytomedicines. Pharmacological and Biochemical Profiling of Lead Compounds from Traditional Remedies. Antihypertensive Peptides from Natural Resources. Xanthones As Therapeutic Agents. Inhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plants extracts and plant-derived compounds. Anticancer Properties of Saffron, Crocus sativus Linn. Lead Compounds and Drug Candidates from Some Turkish Plants for Human Health. Molecular Design of Multifunctional Anti-Salmonella Agents Based on Natural Products. Plant Growth Inhibitory Activities by Secondary Metabolites Isolated from Latin American Flora. Metabolomics Systematic Studies of the Metabolic Profiling