Introduction -- Chemical Kinetics -- Kinetics of Monosubstrate Reactions -- Derivation of Rate Equations -- Linear Inhibition -- Hyperbolic and Parabolic Inhibition -- Enzyme Activation -- Kinetics of Rapid Equilibrium Bisubstrate Reactions -- Steady-State Kinetics of Bisubstrate Reactions -- Kinetic Analysis of Bisubstrate Mechanisms -- Substrate Inhibition and Mixed Dead-End and Product Inhibition -- Trisubstrate Mechanisms -- Cooperative and Allosteric Effects -- The pH Dependence of Enzyme Catalysis -- Effects of Temperature on Enzyme Reactions -- Isotope Exchange -- Kinetic Isotope Effects -- Statistical Analysis of Initial Rate and Binding Data

1. Enzyme kinetics